犬猫细胞学:常见恶性细胞核特点
anisokaryosis(a variation in nuclear size of 1.5 times or greater)
细胞核大小不等(细胞核大小变化在1.5倍或更大倍)pleomorphism (variability in shape between nuclei in a cell population)high or variable N:C ratio(normal, nonlymphoid cells have a N:C ratio of 1:3 to 1:8; ratios of 1:2 or higher suggest malignancy)高的或可变的核质比(正常且非淋巴类细胞核质比在1:3-1:8;核质比在1:2或更高提示恶性)increased mitotic activity(mitotic figures are uncommon in normal tissues)nucleoli that vary in size, shape, and number between cells (variation within the same nucleus is especially significant, as are angular or pointed nucleoli)细胞间细胞核仁大小、形态和数量上的变化(在同一个核里面发生的变化特别显著,像角状或尖状的核仁)coarse chromatin(nuclear material is no longer diffusely scattered throughout the nucleus, but gives the appearance of agglutination)粗糙的染色质(核物质不再呈弥漫分散在核内,而是出现了凝集现象)nuclear molding(compression and deformation of nuclei by other nuclei within the same or adjacent cells)核塑形(在同一个或邻近的细胞内细胞核与另一个细胞核发生了压缩核变形)multinucleation(the presence of 3 or more nuclei within one cell)
Cytology in Veterinary Practice: Sample Collection, Slide Preparation and Interpretation Guidelines